Thrombelastography Guides Transfusion Strategy

Thrombelastography (TEG®): practical considerations on its clinical use in trauma resuscitation

BACKGROUND Thrombelastography is a laboratorial test that measures viscoelastic changes of the entire clotting process. There is growing interest in its clinical use in trauma resuscitation, particularly for managing acute coagulopathy of trauma and assisting decision making concerning transfusion. This review focuses on the clinical use of thrombelastography in trauma, with practical points to...

Thrombelastography Should Be Included in the Algorithm for the Management of Postpartum Hemorrhage.

The impact of early thromboelastography directed therapy in trauma resuscitation

BACKGROUND Conventional coagulation tests do not provide an accurate representation of the complex nature of trauma induced coagulopathy. Thrombelastography provides a prompt global overview of all dynamic sequential aspects of trauma induced coagulopathy. The objective of this study was to evaluate the impact of using thrombelastography on blood products utilization, crystalloids utilization, ...

Cryopreserved deglycerolized blood is safe and achieves superior tissue oxygenation compared with refrigerated red blood cells: a prospective randomized pilot study.

BACKGROUND During preservation, donated liquid red blood cells (RBCs) experience multiple functional and structural changes known as the storage lesion. Increased RBC age is associated with increased infection rates, organ failure, and mortality. METHODS This prospective, randomized, double-blinded pilot study enrolled stable trauma patients who required RBC transfusion. Patients were randoml...

Perioperative Management of a Patient with Glanzmann's Thrombasthenia for Mitral Valve Repair Under Cardiopulmonary Bypass

A 30-year-old male patient presented with Glanzmann's thrombasthenia and mitral valve prolapse. He was in acute decompensated congestive heart failure due to severe mitral and tricuspid regurgitation. After his cardiac failure had been stabilized, the patient was subjected to mitral and tricuspid valve repair. His transfusion requirements were guided by thrombelastography and his bleeding disor...